# Authors Title Journal Year html pdf
37Chung HS, Kim GE, Holewinski, RJ, Venkatraman V, Zhu G, Bedja D, Kass DA, Van Eyk JETransient Receptor Potential Channel 6 Regulates Abnormal Cardiac S-Nitrosylation in Duchenne Muscular DystrophyPNAS2017
36Kirk JA, Kass DACellular and Molecular Aspects of Dyssynchrony and ResynchronizationHeart Fail Clin.2017ViewDownload
35Kim GE, Kass DACardiac Phosphodiesterases and Their Modulation for Treating Heart DiseaseHandbook of Experimental Pharmacology2017ViewDownload
34Kokkonen K, Kass DANanodomain Regulation of Cardiac Cyclic Nucleotide Signaling by Phosphodiesterases.Annu Rev Pharmacol Toxicol2017ViewDownload
33Hsu S, Houston BA, Tampakakis E, Bacher AC, Rhodes PS, Mathai SC, Damico RL, Kolb TM, Hummers LK, Shah AA, McMahan Z, Corona-Villalobos CP, Zimmerman SL, Wigley FM, Hassoun PM, Kass DA, Tedford RJRight Ventricular Functional Reserve in Pulmonary Arterial HypertensionCirculation2016ViewDownload
32Kirk JA, Chakir K, Lee KH, Karst E,Holewinski, RJ, Pironti G, Tunin RS, Pozios I, Abraham TP, de Tombe P, Rockman HA, Van Eyk JE, Craig R, Farazi TG, Kass DA Pacemaker-induced transient asynchrony suppresses heart failure progression Sci Trans Med2015ViewDownload
31Nakamura T, Ranek MA, Lee DI,Shalkey-Hahn V,Kim C, Eaton P, Kass DAPrevention of PKG1 alpha oxidation augments cardioprotection in the stressed heartJ Clin Invest2015ViewDownload
30Lee DI, Zhu G, Sasaki T, Cho GS, Hamdani N, Holewinski R, Jo SH, Danner T, Zhang M, Rainer PP, Bedja D, Kirk JA, Ranek MJ, Dostmann WR, Kwon C, Margulies KB, Van Eyk JE, Paulus WJ, Takimoto E, Kass DAPhosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart diseasNature2015ViewDownload
29Sabbah HN, Tocchetti CG, Wang M, Daya S, Gupta RC, Tunin RS, Mazhari R, Takimoto E, Paolocci N, Cowart D, Colucci WS, Kass DA.Nitroxyl (HNO): A novel approach for the acute treatment of heart failure.Circulation Heart Failure2013ViewDownload
28Kirk JA, Kass DA.Electromechanical dyssynchrony and resynchronization of the failing heart.Circ Res2013ViewDownload
27Tedford RJ, Mudd JO, Girgis RE, Mathai SC, Zaiman AL, Housten-Harris T, Boyce D, Kelemen BW, Bacher AC, Shah AA, Hummers LK, Wigley FM, Russell SD, Saggar R, Saggar R, Maughan WL, Hassoun PM, Kass DA.Right ventricular dysfunction in systemic sclerosis-associated pulmonary arterial hypertension.Circulation Heart Failure2013ViewDownload
26Zhang M, Takimoto E, Lee DI, Santos CX, Nakamura T, Hsu S, Jiang A, Nagayama T, Bedja D, Yuan Y, Eaton P, Shah AM, Kass DA.Pathological cardiac hypertrophy alters intracellular targeting of phosphodiesterase type 5 from nitric oxide synthase-3 to natriuretic peptide signalingCirculation2012ViewDownload
25Cingolani OH, Kirk JA, Seo K, Koitabashi N, Lee DI, Ramirez-Correa G, Bedja D, Barth AS, Moens AL, Kass DAThrombospondin-4 is required for stretch-mediated contractility augmentation in cardiac muscle.Circ Res2011View
24Cingolani OH, Kass DAPressure-volume relation analysis of mouse ventricular function.Am J Physiol Heart Circ Physiol2011View
23Chakir K, Depry C, Dimaano VL, Zhu WZ, Vanderheyden M, Bartunek J, Abraham TP, Tomaselli GF, Liu SB, Xiang YK, Zhang M, Takmoto E, Dulin N, Xiao RP, Zhang J, Kass DAG-alpha(s)-biased beta(2)-adrenergic receptor signaling from restoring synchonous contraction in the failing heartSci Transl Med2011View
21Koitabashi N, Danner T, Zaiman AL, Pinto YM, Rowell J, Mankowski J, Zhang D, Nakamura T, Takimoto E, Kass DAPivotal role of cardiomyocyte TGF-beta signaling in the murine pathological response to sustained pressure overloadJ Clin Invest2011ViewDownload
20Zhang M, Kass DAPhosphodiesterases and cardiac cGMP: evolving roles and controversiesTrends Pharmacol Sci2011View
19Chakir K, Zhu W, Tsang S, Woo AY, Yang D, Wang X, Zeng X, Rhee MH, Mende U, Koitabashi N, Takimoto E, Blumer KJ, Lakatta EG, Kass DA, Xiao RPRGS2 is a primary terminator of beta(2)-adrenergic receptor-mediated G(i) signalingJ Mol Cell Cardiol2011View
18Chakir K, Kass DARethinking resynch: exploring mechanisms of cardiac resynchronization beyond wall motion controlDrug Disc Today Dis Mech2010ViewDownload
17Kass DARes-erection of Viagra as a heart drugCirc Heart Fail2011View
16Zhang M, Takimoto E, Hsu S, Lee DI, Nagayama T, Danner T, Koitabashi N, Barth AS, Bedja D, Gabrielson KL, Wang Y, Kass DAMyocardial remodeling is controlled by myocyte-targeted gene regulation of phosphodiesterase type 5J Am Coll Cardiol2010ViewDownload
15Spragg DD, Dong J, Fetics BJ, Helm R, Marine JE, Cheng A, Henrikson CA, Kass DA, Berger RDOptimal left ventricular endocardial pacing sites for cardiac resynchronization therapy in patients with ishemic cardiomyopathyJ Am Coll Cardiol2010ViewDownload
14Lee DI, Vahebi S, Tocchetti CG, Barouch LA, Solaro RJ, Takimoto E, Kass DAPDE5A suppression of acute beta-adrenergic activation requires modulation of myocyte beta-3 signaling coupled to PKG-mediated troponin I phosphorylationBasic Res Cardiol2010ViewDownload
13Koitabash N, Aiba T, Hesketh GG, Rowell J, Zhang M, Takimoto E, Tomaselli GF, Kass DACyclic GMP/PKG-dependent inhibition of TRPC6 channel activity and expression negatively regulates cardiomyocte NFAT activationJ Mol Cell Cardiol2009View
12Koitabashi N, Bedja D, Zaiman AL, Pinto YM, Zhang M, Gabrielson KL, Takimoto E, Kass DAAvoidance of transient cardiomyopathy in cardiomyocyte-targeted tamoxifen-induced MerCreMer gene deletion modelsCirc Res2009ViewDownload
11Takimoto E, Koitabashi N, Hsu S, Ketner EA, Zhang M, Nagayama T, Bedja D, Gabrielson KL, Blanton R, Siderovski DP, Mendelsohn ME, Kass DARegulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in miceJ Clin Invest2009ViewDownload
10Chakir K, Daya SK, Aiba T, Tunin RS, Dimaano VL, Abraham TP, Lai EW, Pacak K, Zhu WZ, Xiao RP, Tomaselli GF, Kass DAMechanisms of enhanced beta-adrenergic reserve from cardiac resynchronization therapyCirculation2009ViewDownload
9Nagayama T, Hsu S, Zhang M, Koitabashi N, Bedja D, Gabrielson KL, Takimoto E, Kass DASildenafil stops progressive chamber, cellular, and molecular remodeling and improves calcium handling and function in hearts with pre-existing advanced hypertrophy due to pressure-overloadJ Am Coll Cardiol2009ViewDownload
8Zhang M, Koitabashi N, Nagayama T, Rambaran R, Feng N, Takimoto E, Koenke T, O'Rourke B, Champion HC, Crow MT, Kass DAExpression, activity, and pro-hypertrophic effects of PDE5A in cardiac myocytesCellular Signaling2008View
7Moens AL, Takimoto E, Tocchetti CG, Chakir K, Bedja D, Cormaci G, Ketner EA, Majmudar M, Gabrielson K, Halushka MK, Mitchell JB, Biswal S, Channon KM, Wolin MS, Alp NJ, Paolocci N, Champion HC, Kass DAReversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategyCirculation2008ViewDownload
6Chakir K, Daya SK, Tunin RS, Helm RH, Byrne MJ, Dimaano VL, Lardo AC, Abraham TP, Tomaselli GF, Kass DAReversal of global apoptosis and regional stress kinase activation by cardiac resynchronizationCirculation2008ViewDownload
5Mudd JO, Kass DATackling heart failure in the 21st centuryNature2008View
4Nagayama T, Takimoto E, Sadayappan S, Mudd JO, Seidman JG, Robbins J, Kass DAControl of in vivo left-ventricular contraction/relaxation kinetics by myosin binding protein C: protein kinase A phosphorylation dependent and independent regulationCirculation2007ViewDownload
3Melenovsky V, Borlaug BA, Rosen B, Hay I, Ferrucci L, Morell CH, Lakatta EG, Najjar SS, Kass DACardiovascular features of heart failure with preserved ejection fraction versus nonfailing hypertensive left ventricular hypertrophy in the urban Baltimore communityJ Am Coll Cardiol2007ViewDownload
2Takimoto E, Champion HC, Li M, Ren S, Rodriguez ER, Wang Y, Kass DAOxidant stress from nitric oxide synthase-3 uncoupling plays major role in pathologic remodeling to pressure-load cardiac hypertrophyJ Clin Invest2005ViewDownload
1Takimoto E, Champion HC, Li M, Belardi D, Ren S, Rodriguez ER, Bedja D, Gabrielson KL, Wang Y, Kass DAChronic phosphodiesterase 5a inhibition prevents and reverses cardiac hypertrophy independent of systolic loadNature Medicine2005ViewDownload